Mailbag! Docs Using Horse Drugs for Depression?!?

Dear Living Well Daily Reader,

You’ve got questions…

We’ve got answers!

Depression can strike anytime.

And when severe enough it can require medication.

It’s no surprise that some depression drugs can cause all kinds of side effects, but they’re nothing compared to what’s coming down the pike for depression treatment.

You see, a drug with a history of recreational use and addiction issues is now positioned to be the next big depression breakthrough.

Let’s dive in…

Hi Natalie,

I know depression isn’t easy to treat.  But I couldn’t help but be surprised when a friend  (who suffers from severe depression)  recently told me her doctor thinks ketamine would help treat her depression.

This sounds like a bad idea to me. Isn’t ketamine the drug kids are getting high on? Has it ever been used to treat depression?


Sandy C.

Yes, Sandy, you’re right. Ketamine is a popular party drug and is often taken recreationally.

And because it can knock you out cold, it’s even been used in crimes like date rape, kidnapping and robbery.

But it didn’t start out this way.

Ketamine was first used as an anesthetic for large animals. And with good reason — it can drop a half-ton horse to the ground in just a matter of seconds.

It’s now used in humans to help start and maintain anesthesia because it can induce trance-like states. Unfortunately, these trance-like states also come with memory loss, hallucinations and even heart, bowel and psychological problems with long-term use.

But even with these dangerous side effects, some docs are using it as an “off-label” treatment for depression.

You see, after a few positive trials, some physicians have been giving ketamine infusions to treat depression — especially in hard-to-treat cases.

And for some folks it’s worked.

But these results can wear off in as little as a week, so regular infusions are needed to keep depression symptoms in check.

Even worse, there’s yet to be a large-scale trial that can determine whether ketamine is safe and effective for treating depression without any serious side effects.

I don’t know about you, but I would need a lot of good evidence before taking a drug that can put down a horse and cause serious hallucinations.

Not to mention ketamine has addictive properties. This is bad news for everyone but can be especially dangerous for folks already suffering from depression.

Depression is a serious illness and should be treated like one.

But until there’s more proof ketamine is a viable option for depression, there are other ways to fight it.

One good way is with your diet.

Many studies show diet can play a major role in mental health. And a good way to get a grip on your mood is through food.

A good place to start is by reading Food and Mood: Eating Your Way out of Depression. Click here to find out more about it.

Do you have health questions you want answered? Drop me a line:

Live well,

Natalie Moore
Managing editor, Living Well Daily

Ed. Note: Please send your feedback: – and click here to like us on Facebook.


[1] Ketamine

[2] Ketamine depression treatment ‘should be rolled out’

[3] Ketamine For Severe Depression: ‘How Do You Not Offer This Drug To People?’

[4] Ketamine for Depression: Key Efficacy, Safety Questions Remain

Natalie Moore

Written By Natalie Moore

Natalie Moore is a dedicated health researcher with a passion for finding healthy, natural, and science-based solutions. After a decade of direct healthcare experience in western and natural medicine, she was involved in public health research before joining Living Well Daily.

View More Free Articles

The SHOCKING Truth About HIDDEN Antibiotics

I bet you do your best to AVOID unnecessary antibiotics. After all, the overuse of these lifesaving drugs has led to antibiotic resistance. And the result is the emergence of superbugs that can cause dangerous (and even DEADLY) infections that resist all conventional medicines. But what if I told you that you were being force-fed...

Read This

The “No Workout” Method for Getting Fit

You’re not alone if you feel overwhelmed by the thought of adding exercise to your already-packed agenda. In fact, many folks get exhausted just thinking about working out. But if this is you, know that getting fit doesn’t HAVE to feel that way. You can get the benefit of workouts WITHOUT the worry. Here’s how…...

Read This

Common Nutrient Is Colon Cancer’s Kryptonite!?

Experts estimate that in 2024 alone, 611,720 Americans will die from colon cancer. That’s around 1680 souls lost a day. And your risk rises with age. That makes now… BEFORE you or a loved one gets sideswiped with an unexpected diagnosis… the time to think about this deadly disease. After all, one thing no one...

Read This

Mailbag: Knee Pain Solution STOPS the “OUCH!”

“My joints, especially my knees, have been hurting more. What can I do? It’s keeping me from moving a lot.” – Barbara Hi Barbara, It may seem counterintuitive, but carefully chosen exercise could be precisely “what the doctor ordered” to soothe chronic knee pain. Studies show the right activities can EASE the ache, allowing you...

Read This

Ulcer Solution Harnesses the Healing Power of Citrus

No one expects to develop a foot ulcer. That goes without saying. But if you have diabetes, the odds that you will are higher than you might expect. In fact, 60 percent of diabetics will develop neuropathy in their feet, eventually leading to one. However, poor glycemic control isn’t the only trigger for foot ulcers....

Read This

Move More to Hurt Less? Here’s The TRUTH

It’s only natural to avoid moving when you’re in pain. We’ve all been there, gritting our teeth and doing our best to remain still. After all, the last thing you want to do is make the pain WORSE. But this is one time when following your instincts could be a BIG mistake. It could take...

Read This

“Nature Pill” Sends Mental and Physical Health SOARING

A stroll through the park or doing some gardening are enjoyable pastimes for many of us. Unfortunately, they’re ones we often don’t get to do nearly enough. But new research reveals why you should MAKE TIME for these nature-based hobbies. Because, it turns out, as you age your HEALTH could depend on it. Here’s why…...

Read This

“Cold Nose” Method Protects Your Aging Brain

Keeping your mind sharp as you age is a priority. If you’ve been following my suggestions, you may already be taking steps to protect your brain. And that’s fantastic! Things like taking certain supplements, walking regularly, prioritizing quality sleep, doing challenging crossword puzzles, and playing brain-stimulating games can INDEED support brain health and help head...

Read This

Clobber Cold Symptoms and Feel Better FAST

Before leaving on a trip recently my daughter was feeling a bit under the weather. She was worried she might be getting sick and asked how to recover more quickly from a cold. I explained that there’s still no cure for the common cold. But, certain foods and self-care practices CAN ease symptoms and shorten...

Read This

Tasty FAT Hack SLASHES Heart Risk

Is your heart trying to tell you something? Are little warning signs appearing that your ticker may be in trouble someday soon? You may have noticed your blood pressure creeping UP or your energy levels dialing DOWN. Or everyday tasks leave you feeling more winded than usual. Don’t ignore those signs. Your heart could be...

Read This